Search results for "Bromophenol blue"

showing 4 items of 4 documents

Development of an ion-pair to improve the colon permeability of a low permeability drug: Atenolol.

2016

Abstract To ensure the optimal performance of oral controlled release formulations, drug colon permeability is one of the critical parameters. Consequently developing this kind of formulations for low permeability molecules requires strategies to increase their ability to cross the colonic membrane. The objective of this work is to show if an ion-pair formation can improve the colon permeability of atenolol as a low permeability drug model. Two counter ions have been tested: brilliant blue and bromophenol blue. The Distribution coefficients at pH 7.00 (DpH7) of atenolol, atenolol + brilliant blue and atenolol + bromophenol blue were experimentally determined in n-octanol. Moreover, the colo…

DrugMaleColonmedia_common.quotation_subjectPharmaceutical ScienceBromophenol blue02 engineering and technology030226 pharmacology & pharmacyPermeability03 medical and health scienceschemistry.chemical_compound0302 clinical medicinemedicineLow permeabilityAnimalsRats WistarColoring Agentsmedia_commonchemistry.chemical_classificationChromatographyBenzenesulfonates021001 nanoscience & nanotechnologyAtenololPermeability (earth sciences)MembranechemistryAtenololParacellular transportDelayed-Action PreparationsBromphenol BlueCounterion0210 nano-technologymedicine.drugEuropean journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
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Determination of promethazine hydrochloride with bromophenol blue by a turbidimetric method and flow injection analysis

1992

Abstract A flow injection analysis procedure for the turbidimetric determination of promethazine is proposed. The sample solution is injected directly into the carrier reagent stream, which is composed of 1.16 × 10 −3 M bromophenol blue at pH 1.20. The calibration graph is linear over the range 25–197 ppm of promethazine. The influence of some foreign substances was also investigated. The method is applied to promethazine determination in a pharmaceutical formulation.

Flow injection analysisChromatographyCalibration curvePromethazine HydrochlorideBromophenol bluePharmaceutical formulationAnalytical ChemistryPromethazinechemistry.chemical_compoundchemistryReagentmedicineSpectroscopymedicine.drugMicrochemical Journal
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Determination of diphenhydramine hydrochloride by flow injection with Bromophenol Blue and turbidimetric measurement

1990

The study of a number of diphenhydramine-dye systems was carried out in order to determine the most suitable precipitate for the turbidimetric determination of diphenhydramine using flow injection (FI). The reagent selected was Bromophenol Blue. The chemical and FI variables were optimised. The calibration graph was linear over the concentration range 50-230 p.p.m. of diphenhydramine hydrochloride. A number of interfering substances were also investigated.

ChromatographyDiphenhydramine hydrochlorideCalibration curveDiphenhydramineBromophenol blueBiochemistryAnalytical Chemistrychemistry.chemical_compoundDiphenhydraminechemistryNephelometry and TurbidimetryReagentElectrochemistrymedicineEnvironmental ChemistryIndicators and ReagentsBromphenol BlueSpectroscopymedicine.drugThe Analyst
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Haloperoxidase Mimicry by CeO2−xNanorods Combats Biofouling

2016

CeO2-x nanorods are functional mimics of natural haloperoxidases. They catalyze the oxidative bromination of phenol red to bromophenol blue and of natural signaling molecules involved in bacterial quorum sensing. Laboratory and field tests with paint formulations containing 2 wt% of CeO2-x nanorods show a reduction in biofouling comparable to Cu2 O, the most typical biocidal pigment.

Phenol redMechanical EngineeringBromophenol blue02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnologyPhotochemistry01 natural sciences0104 chemical sciencesBiofoulingchemistry.chemical_compoundQuorum sensingPigmentchemistryMechanics of MaterialsHaloperoxidasevisual_artvisual_art.visual_art_mediumEnzyme mimicGeneral Materials ScienceNanorod0210 nano-technologyAdvanced Materials
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